To recognise the two second messenger effects triggered by the postsynaptic effects of ACh upon the different types of muscarinic receptor.

To know that the structure of cholinergic agonists influences their effects and know this relationship determines the clinical uses of cholinergic drugs.

To recognise that muscarinic agonists show little or no selectivity between the subtypes of muscarinic receptor.

To understand that selectivity of action with muscarinic agonists is achieved by a combination of choice of route of administration and the ionised state of the drug.

To know specific examples of cholinergic agonist and antagonists and the conditions for which they are used.