PROFESSOR DAVID HARRISON

• 1. Revise necrosis versus apoptosis

• necrosis = unplanned cell death

• apoptosis = planned cell death which affects one cell

• 2. Understand some key pathways that lead to apoptosis and the importance of balance between pro an anti apoptotic factors; especially the Bcl2 family
• 3. Explain how caspases got their name
• 4. Have an overview of the roles and importance of apoptosis in health and disease
• 5. Define anoikis and pyroptosis
• 6. Know why apoptotic cells are phagocytosed