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In metabolic problems the compensation is respiratory, and faster

An increased anion gap signals the presence of a metabolic acidaemia

in terms of endogenous metabolic causes anything that causes hypovolemia may cause it

such as an embolism or type of shock. Both of which leading to increased anaerobic metabolism and therefore increased lactic acid

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More endogenous causes of metabolic acidemia inc

Ketoacidosis typically caused by unmanaged Diabeties (DKA)

also can be caused by alcohol and stravation

Ketoacidosis causes a raised anion gap

Exogenous causes inc