function of TFPI and Antithrombin - anti-coagulation factors
how many ml of plasma is taken from each donation?
200ml
15ml/kg is the dose given of plasma to patients
tranexamic acid - anti-fibrinolytic drug. it inhibits activation of plasminogen to plasmin it is used in trauma/GI bleeding
pros of warfarin (anticoagulant)
can be reversed by vitamin K
it is cheap
easy measurable test
cons of warfin (anticoagulant)
lots of drug and food interactions to enhance or inhibit effect
slow onset-several days (3-4 days)
unpredictable dose need
needs regular blood testing