guides RNA used to locate (bind) the target DNA to be edited and Cas-9, a protein that essentially cuts the DNA at the location identified by guide RNA. and changes genetic sequences to stop abnormalities, it can be used to implant new donor mitochondria into eggs in ivf of people suffering from mitochondria abnormalities
use of CRISPR in embryos
many people have religious objections for the use of human embryos for research
Use of CRISPR only for those wealthy enough to afford it
this has an ethical and justice concern as only the rich will be able to access such technologies to improve their quality of life. and also it is spread unevenly throughout the world with only wealthy countries having full access
Some worry about informed consent
how can they have truly informed consent if the effects of the therapy are unknown
also some worry that because this is effecting future generations they have not given consent
why risk harming someone, say a child going to be born with albinism who will live a relitively normal and healthy life anyway but why risk that for changing them to be ‘’normal’’ when patients are asked often they say no they are happy the way that they are
some worry about where would the line be drawn on CRISPR help?
right now it is only used for very severe conditions