IgE antibody is used, it is attached to the cell itself and when the antigen binds to the antibody it causes inflammatory responses to occur such as activation of the histamine pathway
IgG antibody predominantly used although IgM is known to be used also.
it works by cell lysis, by complement or phagocytosis can also interfere with cell functions without killing them (cytotoxic)
IgG predominantly but also known to use antibody IgM
antibodies attach to antigens which are soluble and floating in circulation they form antibody-antigen immune complexes can cause conditions such as Serum sickness
T-cell mediated reactions - does not involve antibodies
Helper T-Cells (CD4) attach with antigens to produce a inflammatory response e.g release of TNF-alpha
Killer T-cells (CD8) produce a cytotoxic response and causes cell lysis of antigen affected cells in the body
Type IV hypersensitivity reactions are a type of delayed type hypersensitivity reaction (DTH)
Skin
Systemic sites